ANTIGENS
ANTIGENS AND IMMUNOGENICITY
Question
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In type 1 diabetes the immune cells recognise and respond to proteins on beta cells in the pancreas. These cells produce insulin. The immune response leads to the destruction of the cells, leading to lower levels of insulin. This would be an example of a
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Infectious autoimmune disease
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Non-infectious viral disease
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Infectious viral disease
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Non-infectious autoimmune disease
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Explanation:
Detailed explanation-1: -MECHANISMS OF -CELL DEATH IN TYPE 1 DIABETES. Pancreatic -cells are the target of an autoimmune assault in type 1 diabetes, with invasion of the islets by mononuclear cells in an inflammatory reaction termed “insulitis, ‘’ leading to loss of most -cells after prolonged periods of disease (2).
Detailed explanation-2: -Inside the cells, glucose is stored and later used for energy. With type 1 diabetes, beta cells produce little or no insulin. Without enough insulin, glucose builds up in the bloodstream instead of going into the cells. This buildup of glucose in the blood is called hyperglycemia.
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