ANTIGENS
ANTIGENS AND IMMUNOGENICITY
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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an incomplete antigen
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a complete antigen
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Either A or B
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None of the above
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Detailed explanation-1: -An immunogen can be defined as a complete antigen which is composed of the macromolecular carrier and epitopes (determinants) that can induce immune response. An explicit example is a hapten. Haptens are low-molecular-weight compounds that may be bound by antibodies, but cannot elicit an immune response.
Detailed explanation-2: -A complete antigen is one that both induces an immune response and reacts with the products of it, whereas an incomplete antigen or hapten is unable to induce an immune response alone but is able to react with the products of it, e.g., antibodies.
Detailed explanation-3: -When an antigen binds to a receptor molecule, it may or may not evoke an immune response. Antigens that induce such a response are called immunogens. Thus, it can be said that all immunogens are antigens, but not all antigens are immunogens.
Detailed explanation-4: -An immunogen is a specific type of antigen that is able to elicit an immune response. Antibody development is dependent on a humoral immune response mediated by immune cells recognizing a molecule as being foreign.