IMMUNOLOGY

Detailed explanation-1: -epitope, also called antigenic determinant, portion of a foreign protein, or antigen, that is capable of stimulating an immune response. An epitope is the part of the antigen that binds to a specific antigen receptor on the surface of a B cell.

Detailed explanation-2: -There are three types of epitope: conformational, linear, and discontinuous. This classification is based upon their structure and their interaction with the antibody’s paratope.

Detailed explanation-3: -An antigenic molecule stimulates an immune response. Each specific subset of an antigenic molecule recognized by an antibody or a T cell receptor defines an epitope. Each antigen typically has many epitopes.

Detailed explanation-4: -It is also called antigenic determinants. Autoantigens, for example, are a person’s own self antigens. Examples: Thyroglobulin, DNA, Corneal tissue, etc. Alloantigens are antigens found in different members of the same species (the red blood cell antigens A and B are examples).