IMMUNOLOGY

ANTIGENS

ANTIGENS AND IMMUNOGENICITY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which lymphocyte recognises antigens on the surface of self cells?
A
B-lymphocyte
B
T-lymphocyte
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -The T and B lymphocytes (T and B Cells) are involved in the acquired or antigen-specific immune response given that they are the only cells in the organism able to recognize and respond specifically to each antigenic epitope.

Detailed explanation-2: -In contrast to the immunoglobulins, which interact with pathogens and their toxic products in the extracellular spaces of the body, T cells only recognize foreign antigens that are displayed on the surfaces of the body’s own cells.

Detailed explanation-3: -B cell structure and function During T cell-dependent activation, B cells absorb the antigen and then present pieces of the antigen on their surface via a major histocompatibility complex (MHC). Helper T cells can then recognize those antigens via the MHC and activate the B cells.

Detailed explanation-4: -Unlike B cells, T cells do not directly recognize antigens. Instead, they recognize antigens presented on major histocompatibility complexes ( MHCs ) that cells use to display which proteins are inside of them.

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