IMMUNOLOGY

HYPERSENSITIVITY

CLASSICAL ALTERNATE AND LECTIN PATHWAYS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Allegra, or fexofenadine is what kind of antihistamine?
A
first generation
B
second generation
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -Fexofenadine is a metabolite of terfenadine and is a second-generation antihistamine. It is FDA approved to treat seasonal allergic rhinitis and chronic idiopathic urticaria. Fexofenadine is a medication used to manage and treat allergic rhinitis and chronic urticaria.

Detailed explanation-2: -They can be divided into two categories: first-generation antihistamines and second-and third-generation antihistamines. A common first-generation antihistamine is Benadryl. Second-and third-generation antihistamines include Claritin and Allegra.

Detailed explanation-3: -Fexofenadine, the active metabolite of terfenadine, is a second-generation, highly selective, peripheral histamine H1-receptor antagonist without cardiac effects.

Detailed explanation-4: -Loratadine, cetirizine, and fexofenadine are the most commonly prescribed second-generation antihistamines. Many tests have been conducted to assess the central effects of these three drugs.

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