IMMUNOLOGY

HYPERSENSITIVITY

CLASSICAL ALTERNATE AND LECTIN PATHWAYS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What type of sensitivity is an allergic or atopy reaction?
A
I
B
II
C
III
D
IV
Explanation: 

Detailed explanation-1: -Type I hypersensitivities include atopic diseases, which are an exaggerated IgE mediated immune responses (i.e., allergic: asthma, rhinitis, conjunctivitis, and dermatitis), and allergic diseases, which are immune responses to foreign allergens (i.e., anaphylaxis, urticaria, angioedema, food, and drug allergies).

Detailed explanation-2: -Atopic dermatitis is a type I IgE-mediated hypersensitivity reaction, but the exact etiology is unknown.

Detailed explanation-3: -Atopy is a predisposition to an immune response against diverse antigens and allergens leading to CD4+ Th2 differentiation and overproduction of immunoglobulin E (IgE). The clinical consequence is an increased propensity to hypersensitivity reactions.

Detailed explanation-4: -rash. flushing. hives. itching. edema. wheezing. rhinitis. stomach cramps. 14-Oct-2021

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