HYPERSENSITIVITY
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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In a person who is not experiencing a type I hypersensitivity or infection with worms, is the concentration of IgE high or low in concentration in the blood serum?
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high
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low
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Either A or B
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None of the above
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Explanation:
Detailed explanation-1: -Low serum IgE has been associated clinically with chronic fatigue and polyarthralgias 8 and a higher prevalence of autoimmune and oncological diseases and asthma, as well as chronic sinusitis and otitis media 9.
Detailed explanation-2: -Type I hypersensitivity is also known as an immediate reaction and involves immunoglobulin E (IgE) mediated release of antibodies against the soluble antigen. This results in mast cell degranulation and release of histamine and other inflammatory mediators.
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