HYPERSENSITIVITY
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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GM-CSF
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TH2
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Either A or B
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None of the above
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Detailed explanation-1: -GM-CSF also has an important cytokine effect in chronic inflammatory diseases by stimulating the activation and migration of myeloid cells to inflammation sites, promoting survival of target cells and stimulating the renewal of effector granulocytes and macrophages.
Detailed explanation-2: -The CSF family includes: G-CSF stimulates the production of polymorphonuclear (PMN ) leukocytes, which are necessary for the ingestion and intracellular destruction of bacteria. It is often used to increase neutrophil numbers and decrease infections in patients with non-myeloid malignancies.
Detailed explanation-3: -Granulocyte colony-stimulating factor (G-CSF) primarily increases the production and function of neutrophils by stimulating the proliferation of committed myeloid precursors, rather than pluripotential stem cells [1].