IMMUNOLOGY

HYPERSENSITIVITY

CLASSICAL ALTERNATE AND LECTIN PATHWAYS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Infants with eczema and children deficient in ____ support the hygiene hypothesis.
A
filaggrin
B
keratin
C
melanin
D
carotene
Explanation: 

Detailed explanation-1: -Causes of filaggrin deficiency Skin inflammation (e.g., from atopic dermatitis or psoriasis), which can cause a decrease in the natural production of filaggrin and the enzyme that breaks down filaggrin into water-binding amino acids.

Detailed explanation-2: -Eczema is caused by problems with the skin barrier. Many children with eczema do not have enough of a special protein called “filaggrin” in the outer layer of skin. Filaggrin helps skin form a strong barrier between the body and the environment.

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