HYPERSENSITIVITY
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Type I
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Type II
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Type III
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Type I
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Detailed explanation-1: -Examples of Type II hypersensitivity reactions include blood transfusion reactions, erythroblastosis fetalis, and autoimmune hemolytic anemia.
Detailed explanation-2: -In type III hypersensitivity reactions, an abnormal immune response is mediated by the formation of antigen-antibody aggregates called “immune complexes."[1] They can precipitate in various tissues such as skin, joints, vessels, or glomeruli and trigger the classical complement pathway.
Detailed explanation-3: -Examples of type II HS include some forms of anemia, blood transfusion reactions, certain platelet disorders, and some types of tissue transplant rejection.
Detailed explanation-4: -Type II hypersensitivity reactions (Fig. 46-2) are caused by chemical modification of cell surface or matrix-associated antigens that generates “foreign” epitopes to which the immune system is not tolerant.