HYPERSENSITIVITY
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Vasodilation following a type I hypersensitivity reaction is principally caused by which molecule?
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Histamine
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Leukotrine
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Bradykine
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Tryptase
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Explanation:
Detailed explanation-1: -Type I hypersensitivity is also known as an immediate reaction and involves immunoglobulin E (IgE) mediated release of antibodies against the soluble antigen. This results in mast cell degranulation and release of histamine and other inflammatory mediators.
Detailed explanation-2: -Histamine stimulates vasodilation, and increases vascular permeability, heart rate, cardiac contraction, and glandular secretion.
Detailed explanation-3: -Immediate hypersensitivity Within minutes of skin contact by an antigen, the mast cells release histamine and other factors, causing an inflammatory reaction. Both immunologic and non-immunologic type I reactions were proposed by Maibach & Johnson (1975).
There is 1 question to complete.