IMMUNOLOGY

HYPERSENSITIVITY

CLASSICAL ALTERNATE AND LECTIN PATHWAYS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What antibody or cell involved in Type IV hypersensitivity reaction?
A
Ig G
B
TH 1
C
TH 2
D
Basophil
E
Macrophage
Explanation: 

Detailed explanation-1: -A Type IV hypersensitivity reaction is mediated by T cells that provoke an inflammatory reaction against exogenous or endogenous antigens.

Detailed explanation-2: -Type IV hypersensitivity is also known as delayed-type and involves of T-cell-mediated reactions. T-cells or macrophages are activated as a result of cytokine release, leading to tissue damage.

Detailed explanation-3: -Immediate hypersensitivity reactions are predominantly mediated by IgE, IgM, and IgG antibodies.

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