IMMUNOLOGY

HYPERSENSITIVITY

CLASSICAL ALTERNATE AND LECTIN PATHWAYS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following effects is NOT a result of histamine binding to histamine receptor H1?
A
intestinal smooth muscle contraction
B
suppression of mast cell degranulation
C
increased vascular permeability
D
increased mucous secretion
E
all of the answers result from histamine binding H1
Explanation: 

Detailed explanation-1: -The following are the major consequences of H1 receptor stimulation: Capillary and venous dilation, which can produce marked hypotension. In the skin, histamine contributes to the wheal-and-flare response; an axon reflex via H1 receptors is responsible for the spread of vasodilation or flare from the oedematous wheal.

Detailed explanation-2: -The message is, “Release histamines, ‘’ which are stored in the mast cells. When they leave the mast cells, histamines boost blood flow in the area of your body the allergen affected. This causes inflammation, which lets other chemicals from your immune system step in to do repair work.

There is 1 question to complete.