HYPERSENSITIVITY
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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skin epithelial cells
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intestinal epithelial cells
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Either A or B
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None of the above
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Detailed explanation-1: -Th2 cells and/or their secreted effector molecules mediate the immune response to allergens and are triggered by exposure to specific allergens leading to allergic asthma.
Detailed explanation-2: -Dendritic cells are key initiators and master regulators of the allergen-specific immune response by processing and presenting antigens to Tconv and secreting cytokines that control T cell differentiation to a certain effector type.
Detailed explanation-3: -Basophils and mast cells Mast cells are located in tissues, mainly in mucosa, and their granules contain heparin, serotonin, and histamine. They may also release a variety of cytokines that enhance the inflammatory process, especially during the early events. These cells are involved in allergic and viral processes.