IMMUNE RESPONSE
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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A proteoglycan which serves to assemble a complex containing granzymes and perforin is known as?
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Serglycin
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Cytokine
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Cytotoxic T-Cell
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Cytotoxic B-Cell
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Explanation:
Detailed explanation-1: -Granzymes are a family of serine proteases stored in granules inside cytotoxic cells of the immune system. Granzyme K (GrK) has been only limitedly characterized and knowledge on its molecular functions is emerging. Traditionally GrK is described as a granule-secreted, pro-apoptotic serine protease.
Detailed explanation-2: -CTL and NK cell granules contain perforin and granzymes The lytic granules contain the pore-forming protein perforin and a series of granule-associated enzymes, called granzymes.
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