IMMUNOLOGY

IMMUNE RESPONSE

CLASSICAL ALTERNATE AND LECTIN PATHWAYS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which one is not associated with Natural Killer cells?
A
Does not acquire immune memory after initial exposure to antigen
B
Amplify inflammatory response after bacterial infection
C
Possess CD16, CD56 and CD3 surface proteins
D
Major early role in recognizing and killing virus-infected host cells and tumor cells
Explanation: 

Detailed explanation-1: -NATURAL killer (NK) cells are large granular lymphocytes capable of killing tumour cells in a non-MHC restricted manner1, 2. NK cells do not express cell-surface CD3, or any known target recognition structure analogous to the T cell antigen receptor (TCR) heterodimers ( or )3–8.

Detailed explanation-2: -The CD56dim CD16bright NK cells represent at least 90% of all peripheral blood NK cells and are therefore the major circulating subset. A maximum of 10% are CD56bright NK cells. The various subsets can easily be distinguished by flow cytometry as depicted in Fig.

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