IMMUNE RESPONSE
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Plasma Cell
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Memory B-Cell
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Common B-Cell
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Activated Helper T-Cell
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Detailed explanation-1: -Ig heavy chain class switching occurs rapidly after activation of mature naïve B cells, resulting in a switch from expressing IgM and IgD to expression of IgG, IgE, or IgA; this switch improves the ability of antibodies to remove the pathogen that induces the humoral immune response.
Detailed explanation-2: -During class switch recombination the constant region portion of the antibody-heavy chain is changed, but the variable region of the heavy chain stays the same; thus, class switching does not affect antigen specificity.
Detailed explanation-3: -IgM is not only the first class of antibody to appear on the surface of a developing B cell. It is also the major class secreted into the blood in the early stages of a primary antibody response, on first exposure to an antigen.