IMMUNOLOGY

Detailed explanation-1: -The bone marrow is the site of neutrophil production, a process that is regulated by the cytokine granulocyte colony-stimulating factor (G-CSF). Mature neutrophils are continually released into the circulation, with an estimated 1011 neutrophils exiting the bone marrow daily under basal conditions.

Detailed explanation-2: -Once your white blood cells pass basic training in your bone marrow, your immune system sends their troops of mature cells (neutrophils, eosinophils and basophils) to travel through your circulation system and tissues to prepare for invaders that cause illness, infection and disease.