IMMUNOLOGY

Detailed explanation-1: -Artificial opsonin is a therapeutic strategy to enhance phagocytosis in immunocompromised patients and patients infected with antibiotic-resistant pathogens.

Detailed explanation-2: -Interestingly, IgM, IgA and IgG1 can promote the phagocytosis of C. neoformans through complement receptors in the absence of complement; this occurs because of an antibody-mediated change in the organism’s capsule that allows an interaction with complement receptors (126).

Detailed explanation-3: -The main function of immunoglobulins is to react against antigens in order to mediate their elimination. Immunoglobulins react with antigens in two different ways: Bound to B lymphocytes forming the BcR receptor, which allows their reaction with antigens in their native form.