IMMUNE RESPONSE
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Name the cytokine:Activates NK, CD4 TH1 cells
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IL-12
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IL-10
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IL-8
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MIF
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Explanation:
Detailed explanation-1: -IL-12 is the prototypical innate cytokine capable of activating NK cells, and it acts synergistically with several other cytokines to elicit the production of IFN-.
Detailed explanation-2: -Th1 cells are the principal mediators of immunity that eradicate intracellular pathogens and tumors. Their major effector cytokine is IFN-. IFN- from Th1 cells stimulates macrophages to phagocytose and generate oxidative bursts that aid intracellular killing of microbes.
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