IMMUNE RESPONSE
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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CTL
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NK
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CTL and NK
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CTL and NK and Macrophages
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Detailed explanation-1: -Cytotoxic T cells can kill their targets rapidly because they store preformed cytotoxic proteins in forms that are inactive in the environment of the lytic granule.
Detailed explanation-2: -Natural killer (NK) cells kill cancer cells by secreting perforins and granzymes. Upon contact with cancer cells, NK cells form immune synapses to deliver the lethal hit. Mature NK cells are differentiated from hematopoietic stem cells in the bone marrow.
Detailed explanation-3: -What is the difference between cytotoxic T-cells and natural killer cells? Cytotoxic T-cells attack viruses when activated by an antigen. Natural killer cells don’t need activation to attack harmful cells.
Detailed explanation-4: -Cytotoxins go directly inside the cell through this pore, destroying it and any viruses inside. This is why Killer T-cells are also called Cytotoxic T-cells. The pieces of destroyed cells and viruses are then cleaned up by macrophages.