IMMUNOLOGY

IMMUNE RESPONSE

CLASSICAL ALTERNATE AND LECTIN PATHWAYS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which dendritic cell is located in the liver?
A
Kupffer cells
B
Interdigitating Dendritic cells
C
Langerhans cells
D
Microglial cells
Explanation: 

Detailed explanation-1: -Among the hepatic immune cells, the hepatic dendritic cells (HDCs), uniquely, have a migratory capacity, produce particular cytokines and promote the adaptive immune system response and acts as a bridge between the innate and adaptive process (22).

Detailed explanation-2: -Kupffer cells are involved in the defence against infections of the liver. Their major role in the host defence and the prognosis of liver infection is indicated by studies in experimental models of sepsis.

Detailed explanation-3: -Abstract. Kupffer cells are liver macrophages abundantly resident in the sinusoids and are the largest tissue-resident macrophage population. They may arise from resident progenitor cells or infiltrating myeloid cells.

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