IMMUNOGLOBULINS
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
Question
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Complement plays a major role in several disease states. Decreased complement levels or a decline in lytic activity can indicate either hereditary deciencies or extreme activation of the system.
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First statement is true; Second statement is false
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First statement is false; Second statement is true
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Both statements are true
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Both statements are false
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Explanation:
Detailed explanation-1: -The complement system has four major function, including lysis of infectious organisms, activation of inflammation, opsonization and immune clearance.
Detailed explanation-2: -The main role of complement in pathogen elimination is indirect, namely, the deposition of complement fragments on the surface of pathogen targets, so-called opsonization that allows their recognition, ingestion, and destruction by phagocytic cells, neutrophils, monocytes, and macrophages (Figure 3B).
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