IMMUNOLOGY

IMMUNOGLOBULINS

CLASSICAL ALTERNATE AND LECTIN PATHWAYS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Complement plays a major role in several disease states. Decreased complement levels or a decline in lytic activity can indicate either hereditary deciencies or extreme activation of the system.
A
First statement is true; Second statement is false
B
First statement is false; Second statement is true
C
Both statements are true
D
Both statements are false
Explanation: 

Detailed explanation-1: -The complement system has four major function, including lysis of infectious organisms, activation of inflammation, opsonization and immune clearance.

Detailed explanation-2: -The main role of complement in pathogen elimination is indirect, namely, the deposition of complement fragments on the surface of pathogen targets, so-called opsonization that allows their recognition, ingestion, and destruction by phagocytic cells, neutrophils, monocytes, and macrophages (Figure 3B).

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