IMMUNOGLOBULINS
IMMUNOGLOBULIN STRUCTURE TYPES DISTRIBUTION BIOLOGICAL AND CHEMICAL PROPERTIES
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Question
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The light chains are encoded by either kappa or lambda. These genes consists of different segments that encoded for the variable and constant domain. They are
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C-J-V
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V-J-C
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J-V-C
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None
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Explanation:
Detailed explanation-1: -The light-chain variable region is composed of only two gene segments: V and J. Genes for the V and J segments of light chains are located on chromosome 2 in humans.
Detailed explanation-2: -To make an antibody molecule, a VL gene segment recombines with a JL gene segment to produce a DNA sequence coding for the V region of a light chain, and a VH gene segment recombines with a D and a JH gene segment to produce a DNA sequence coding for the V region of a heavy chain.
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