IMMUNOGLOBULINS
IMMUNOGLOBULIN STRUCTURE TYPES DISTRIBUTION BIOLOGICAL AND CHEMICAL PROPERTIES
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Question
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Type I
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Type II
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Type III
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Type IV
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Detailed explanation-1: -Type I hypersensitivities include atopic diseases, which are an exaggerated IgE mediated immune responses (i.e., allergic: asthma, rhinitis, conjunctivitis, and dermatitis), and allergic diseases, which are immune responses to foreign allergens (i.e., anaphylaxis, urticaria, angioedema, food, and drug allergies).
Detailed explanation-2: -The most common diseases involving a type III hypersensitivity reaction are serum sickness, post-streptococcal glomerulonephritis, systemic lupus erythematosus, farmers’ lung (hypersensitivity pneumonitis), and rheumatoid arthritis.
Detailed explanation-3: -Exposure to poison ivy resulting in contact dermatitis is a classic example.[4] Several drugs (antibiotics, anticonvulsants) can trigger type IV hypersensitivity reactions leading to drug hypersensitivity and other clinical syndromes.