IMMUNOGLOBULINS
MONOCLONAL ANTIBODIES
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Antibodies made from phagocytes.
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Antibodies from cells that are cloned from one cell.
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Antibodies cloned from lots of cells.
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Antibodies made by tumour cells.
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Detailed explanation-1: -A monoclonal antibody is a homogeneous antibody derived from a single B-cell clone which detects a single epitope within the immunogen. All monoclonal antibodies begin as a pool of polyclonal antibodies but are isolated through a selection or cloning process to identify and expand the desired monovalent clone.
Detailed explanation-2: -Monoclonal antibodies are antibodies which are produced by a single clone of a specific white blood cell. They are specific to one binding site on one protein antigen (the molecules that are found on the surface of pathogens) so they are able to target specific cells.
Detailed explanation-3: -Monoclonal antibodies (mAbs) are generated by identical B cells which are clones from a single parent cell. This means that the monoclonal antibodies have monovalent affinity and only recognize the same epitope of an antigen.