IMMUNOLOGY

Detailed explanation-1: -Hybridoma technology is one of the most common methods used to produce monoclonal antibodies. In this process, antibody-producing B lymphocytes are isolated from mice after immunizing the mice with specific antigen and are fused with immortal myeloma cell lines to form hybrid cells, called hybridoma cell lines.

Detailed explanation-2: -Hybridomas are cells formed via fusion between a short-lived antibody-producing B cell and an immortal myeloma cell. Each hybridoma constitutively expresses a large amount of one specific mAb, and favored hybridoma cell lines can be cryopreserved for long-lasting mAb production.

Detailed explanation-3: -Hybridoma technology overview Hybridoma cells are generated via fusion between a short-lived antibody-producing B cell and an immortal myeloma cell.

Detailed explanation-4: -hybrid cell, known as a hybridoma, multiplies rapidly in culture. Since the antibodies obtained from hybridomas are produced by clones derived from a single lymphocyte, they are called monoclonal antibodies.