IMMUNOLOGY

MISCELLENOUS

VACCINATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
____ is a measure of the strength of the binding of 1 Fab region with its corresponding epitope on the antigen.
A
Affinity
B
Avidity
C
Equivalence
D
Post zone
Explanation: 

Detailed explanation-1: -Affinity is the strength required for an interaction between a site of antigen binding at an antibody and an antigen epitope.

Detailed explanation-2: -The strength of binding of one Fab on an immunoglobulin to one epitope on an antigen is referred to as. Prozone. A situation in which antibody is in excess as compared to antigen is called. Precipitation.

Detailed explanation-3: -Antibody affinity is defined as strength of the binding interaction between antigen and antibody.

Detailed explanation-4: -Avidity describes the measure of overall or accumulated strength of a protein-protein complex, i.e. The total strength of all the non-covalent interactions between an antibody binding to its ligand/s. It is determined by three parameters: The binding affinity of the complex. The valency of the proteins.

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