IMMUNOLOGY

Detailed explanation-1: -Neutrophils are the most abundant leukocytes in the blood and they lead the first wave of host defense to infection or tissue damage. Neutrophils are powerful effector cells that destroy infectious threats through phagocytosis, degranulation, reactive oxygen species (ROS) and neutrophil extracellular traps1–3.

Detailed explanation-2: -Neutrophils are known to be the first cells to reach the site of inflammation and their chemotaxis to the site of inflammation is the critical immune response process in the management of tissue infection and injury. Neutrophils have complex functions.

Detailed explanation-3: -Neutrophils are the first WBC population to arrive and affect the host inflammatory response during exercise and soft tissue injury ( Table). These cells have both specific and nonspecific defensive mechanisms, some of which are capable of causing additional tissue damage.