IMMUNOLOGY

Detailed explanation-1: -Skin, tears and mucus are part of the first line of defence in fighting infection. They help to protect us against invading pathogens. You have beneficial bacteria growing on your skin, in your bowel and other places in the body (such as the mouth and the gut) that stop other harmful bacteria from taking over.

Detailed explanation-2: -As a protective interface between internal organs and the environment, the skin encounters a host of toxins, pathogenic organisms, and physical stresses. To combat these attacks on the cutaneous microenvironment, the skin functions as more than a physical barrier: it is an active immune organ.

Detailed explanation-3: -The first line of defense against infection are the surface barriers that prevent the entry of pathogens into the body. The second line of defense are the non-specific phagocytes and other internal mechanisms that comprise innate immunity.

Detailed explanation-4: -First line of defense: Owns and manages risks/risk owners/managers. Second line of defense: Oversees risks/risk control and compliance. Third line of defense: Provides independent assurance/risk assurance.