IMMUNOLOGY

Detailed explanation-1: -At the same time, neutrophils release reactive oxygen species and cytokines outside the cells to kill extracellular bacteria and recruit additional leukocytes to the region of infection or inflammation.

Detailed explanation-2: -When activated, neutrophils release macrophage inflammatory protein-1 (MIP-1), MIP-1 and IFN- [18].

Detailed explanation-3: -Neutrophil serine proteases are granule-associated enzymes known mainly for their function in the intracellular killing of pathogens. Their extracellular release upon neutrophil activation is traditionally regarded as the primary reason for tissue damage at the sites of inflammation.

Detailed explanation-4: -Neutrophils help prevent infections by blocking, disabling, digesting, or warding off invading particles and microorganisms. They’re constantly searching for signs of infection, and quickly respond to trap and kill pathogens.