MISCELLENOUS
VACCINATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Multiple myeloma
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SCID
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Hodgkins
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Non Hodgkins
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Detailed explanation-1: -In myeloma, large amounts of a single antibody are noted as a “monoclonal immunoglobulin spike” or “monoclonal spike” (M spike), indicating that the protein came from cells that originally started as single, malignant cell.
Detailed explanation-2: -A monoclonal spike (M spike or paraprotein) on serum protein electrophoresis (SPEP) is a frequent finding in the general population and typically is pathognomonic of an asymptomatic, premalignant condition called monoclonal gammopathy of undetermined significance (MGUS).
Detailed explanation-3: -Increased gamma globulin proteins may indicate: Blood cancers, including multiple myeloma, Waldenström macroglobulinemia, lymphomas, and chronic lymphocytic leukemias. Chronic inflammatory disease (for example, rheumatoid arthritis)