IMMUNOLOGY

Detailed explanation-1: -Cell components encompass phagocytic cells, epithelial and endothelial cells, natural killer cells, innate lymphoid cells, and platelets (Figure 1). Phagocytic cells consist of granulocytes (i.e., neutrophils, eosinophils, basophils, and mast cells), monocytes/macrophages, and dendritic cells.

Detailed explanation-2: -Granulocytes are a key component of the innate immune system (ie, nonspecific immune defense system). The granulocyte network includes 3 main components: neutrophils, eosinophils, and basophils. This network makes up 50% of the body’s circulating WBCs.

Detailed explanation-3: -The innate immune system can be categorized into three defense mechanisms: (1) physical barriers, (2) cellular components, and (3) humoral responses (15). As will be discussed, the functions of these defense mechanisms are highly conserved between fish and mammals.