IMMUNOLOGY

Detailed explanation-1: -Mast cells are very similar to basophil granulocytes (a class of white blood cells) in blood. Both are granulated cells that contain histamine and heparin, an anticoagulant. Their nuclei differ in that the basophil nucleus is lobated while the mast cell nucleus is round.

Detailed explanation-2: -Activated basophils and mast cells release both overlapping and unique sets of inflammatory mediators, including histamine, proteoglycans, lipid mediators, proteases, chemokines, growth factors and cytokines [9].