MISCELLENOUS
VACCINATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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which among the following has pentameric structure
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IgM
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IgG
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IgA
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IgD
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Explanation:
Detailed explanation-1: -In contrast, IgM from bony fish predominantly forms a tetramer structure, whereas the IgM produced by cartilaginous fish, such as shark, are pentameric in structure [15, 16].
Detailed explanation-2: -IgM antibodies are found mainly in blood; they are pentameric in structure. IgM is specialized to activate complement efficiently upon binding antigen.
Detailed explanation-3: -The IgM molecule possesses a double heterodimeric structure, consisting of two identical heavy (H) (2) and two identical or light (L2) chains. In healthy humans, the predominant polymer is the pentamer (2, L2)5, with a molecular weight of 970 kDa and a sedimentation rate of approximately 19 S.
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