IMMUNOLOGY

Detailed explanation-1: -The red bone marrow produces B-lymphocytes (B cells) and T lymphocytes (T cells). B cells achieve immunocompetence (ability to recognize a specific antigen) in bone marrow. T cells migrate to the thymus gland, where they become immunocompetent.

Detailed explanation-2: -The cells that develop the ability to carry out immune responses (immunocompetence) are lymphocytes called B cells and T cells. Both develop from pluripotent stem cells that originate in red bone marrow.

Detailed explanation-3: -Produced in the bone marrow, B cells migrate to the spleen and other secondary lymphoid tissues where they mature and differentiate into immunocompetent B cells.

Detailed explanation-4: -B cells change their location with their stages of maturation, each location providing the microenvironment suitable for the B cell at that life stage. Stem cells produce lymphoid progenitors and pro-B cells in the marrow just under the bone. Developing B cells move toward the center of the marrow as they mature.

Detailed explanation-5: -In reference to lymphocytes, immunocompetence means that a B cell or T cell is mature and can recognize antigens and allow a person to mount an immune response.

Detailed explanation-6: -B-lymphocytes develop immunocompetence in the bone marrow. The B-lymphocytes or B-cells originate and mature and develop immunocompetence in the bone marrow.