IMMUNOLOGY

Detailed explanation-1: -The therapeutic serum developed by Behring prevented diphtheria for only a short period of time. In 1901, Behring, therefore, for the first time, used a diphtheria innoculation of bacteria with reduced virulence. With this active immunization he hoped to help the body also produce antitoxins.

Detailed explanation-2: -Emil von Behring and other researchers showed that by means of blood plasma, or serum, antibodies could be transferred from one person or animal to another person, who also then became immune. In 1900 Behring introduced serum from immune horses as a method to cure and prevent diphtheria.

Detailed explanation-3: -A century ago, Emil von Behring passed away. He was the first to be honored by the Nobel Prize for Medicine in 1901 for the successful therapy of diphtheria and tetanus, which he had developed from the bench to the bed.

Detailed explanation-4: -The bacterium was first observed in diphtheritic membranes by Edwin Klebs in 1883 and cultivated by Friedrich Löffler in 1884. Beginning in the early 1900s, prophylaxis was attempted with combinations of toxin and antitoxin.