OVERVIEW OF THE IMMUNE SYSTEM
IMMUNITY INNATE AND ADAPTIVE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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delayed response
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immediate or acute response
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immunodefiency
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auto-immune disease
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Detailed explanation-1: -Immediate hypersensitivity reactions are predominantly mediated by IgE, IgM, and IgG antibodies.
Detailed explanation-2: -Type I reactions (i.e., immediate hypersensitivity reactions) involve immunoglobulin E (IgE)–mediated release of histamine and other mediators from mast cells and basophils. Examples include anaphylaxis and allergic rhinoconjunctivitis.
Detailed explanation-3: -Type II hypersensitivity reaction refers to an antibody-mediated immune reaction in which antibodies (IgG or IgM) are directed against cellular or extracellular matrix antigens, resulting in cellular destruction, functional loss, or tissue damage.
Detailed explanation-4: -Type I hypersensitivity is also known as an immediate reaction and involves immunoglobulin E (IgE) mediated release of antibodies against the soluble antigen. This results in mast cell degranulation and release of histamine and other inflammatory mediators.
Detailed explanation-5: -In type III hypersensitivity reactions, an abnormal immune response is mediated by the formation of antigen-antibody aggregates called “immune complexes."[1] They can precipitate in various tissues such as skin, joints, vessels, or glomeruli and trigger the classical complement pathway.
Detailed explanation-6: -Type I: reaction mediated by IgE antibodies. Type II: cytotoxic reaction mediated by IgG or IgM antibodies. Type III: reaction mediated by immune complexes. Type IV: delayed reaction mediated by cellular response. 06-Mar-2023