IMMUNOLOGY

OVERVIEW OF THE IMMUNE SYSTEM

IMMUNITY INNATE AND ADAPTIVE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
B-lymphocytes convert to ____ and then produce or become ____, which oversee humoral immunity.
A
plasma cells; t-lymphocytes
B
t-lymphocytes; plasma cells
C
plasma cells; antibodies
D
plasma cells; antigens
Explanation: 

Detailed explanation-1: -B lymphocytes or B cells produce antibodies involved in humoral immunity. B cells are produced in the bone marrow, where the initial stages of maturation occur, and travel to the spleen for final steps of maturation into naïve mature B cells.

Detailed explanation-2: -The B Cells have the ability to transform into plasmocytes and are responsible for producing antibodies (Abs). Thus, humoral immunity depends on the B Cells while cell immunity depends on the T Cells.

Detailed explanation-3: -Plasma cells, also called plasma B cells or effector B cells, are white blood cells that originate in the lymphoid organs as B lymphocytes and secrete large quantities of proteins called antibodies in response to being presented specific substances called antigens.

Detailed explanation-4: -B lymphocytes play a critical role in pathogen-specific immunity by producing antibodies. B lymphocytes recognize soluble antigens via immunoglobulins anchored on their surface and differentiate into antibody-producing cells, called plasma cells, capable of secreting immunoglobulins.

Detailed explanation-5: -Plasma cells are differentiated B-lymphocyte white blood cells capable of secreting immunoglobulin, or antibody. These cells play a significant role in the adaptive immune response, namely, being the main cells responsible for humoral immunity.

Detailed explanation-6: -Humoral adaptive immunity is a form of adaptive immunity whereby B-lymphocytes and plasma cells (effector b cells) produce antibodies against foreign agents (antigens) and stimulate T-lymphocytes to attack them. This type of immunity is mediated by antibodies.

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