IMMUNOLOGY

OVERVIEW OF THE IMMUNE SYSTEM

LYMPHOCYTE SUBPOPULATION IN HUMANS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which one of the following MHCs involved in CTLs in cancer immunology
A
MHC I
B
MHC II
C
MHC III
D
MHC IV
Explanation: 

Detailed explanation-1: -The major histocompatibility (MHC) class I antigen presentation pathway plays an important role in alerting the immune system to virally infected cells. MHC class I molecules are expressed on the cell surface of all nucleated cells and present peptide fragments derived from intracellular proteins.

Detailed explanation-2: -As part of the positive selection process in the thymus, developing T cells that express receptors recognizing class I MHC proteins are selected to become cytotoxic cells, while T cells that express receptors recognizing class II MHC proteins are selected to become helper cells.

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