OVERVIEW OF THE IMMUNE SYSTEM
MACROPHAGES
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which is the third step in phagocytosis?
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Chemotaxis
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Engulfment
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Phagosyme-lysosome fusion
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Destruction
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Explanation:
Detailed explanation-1: -In the final step, the phagosome fuses with the cell’s lysosomes, forming a phagolysosome which functions to finally destroy the pathogen. Acidification of phagosomes is an important part of phagocytosis.
Detailed explanation-2: -Activation. Resting phagocytes become activated by inflammatory mediators (e.g. bacterial proteins, capsules, peptidoglycan, prostaglandins, complement proteins). Chemotaxis. Margination, Rolling and Adhesion. Diapedesis. Recognition-Attachment. Phagocytosis.
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