IMMUNOLOGY

OVERVIEW OF THE IMMUNE SYSTEM

MACROPHAGES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is step four in phagocytosis?
A
Chemotaxis
B
Engulfment
C
Phagosyme-lysosome fusion
D
Destruction
Explanation: 

Detailed explanation-1: -The main types of phagocytes are monocytes, macrophages, neutrophils, tissue dendritic cells, and mast cells.

Detailed explanation-2: -The process of phagocytosis involves several phases: i) detection of the particle to be ingested, ii) activation of the internalization process, iii) formation of a specialized vacuole called phagosome, and iv) maturation of the phagosome to transform it into a phagolysosome.

Detailed explanation-3: -Phagocytosis involves a series of steps from recognition of the target particle, ingestion of it in a phagosome (phagocytic vacuole), maturation of this phagosome into a phagolysosome, to the final destruction of the ingested particle in the robust antimicrobial environment of the phagolysosome.

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