OVERVIEW OF THE IMMUNE SYSTEM
MACROPHAGES
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Chemotaxis
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Engulfment
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Phagosyme-lysosome fusion
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Destruction
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Detailed explanation-1: -The main types of phagocytes are monocytes, macrophages, neutrophils, tissue dendritic cells, and mast cells.
Detailed explanation-2: -The process of phagocytosis involves several phases: i) detection of the particle to be ingested, ii) activation of the internalization process, iii) formation of a specialized vacuole called phagosome, and iv) maturation of the phagosome to transform it into a phagolysosome.
Detailed explanation-3: -Phagocytosis involves a series of steps from recognition of the target particle, ingestion of it in a phagosome (phagocytic vacuole), maturation of this phagosome into a phagolysosome, to the final destruction of the ingested particle in the robust antimicrobial environment of the phagolysosome.