OVERVIEW OF THE IMMUNE SYSTEM
THE GOOD BAD AND UGLY OF THE IMMUNE SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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major histocompatibility complex (MHC)
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variable regions of antibodies
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operons
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regulatory sequences
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Detailed explanation-1: -major histocompatibility complex (MHC), group of genes that code for proteins found on the surfaces of cells that help the immune system recognize foreign substances. MHC proteins are found in all higher vertebrates. In human beings the complex is also called the human leukocyte antigen (HLA) system.
Detailed explanation-2: -The major histocompatibility complex (MHC) of genes consists of a linked set of genetic loci encoding many of the proteins involved in antigen presentation to T cells, most notably the MHC class I and class II glycoproteins (the MHC molecules) that present peptides to the T-cell receptor.
Detailed explanation-3: -The major Histocompatibility Complex (MHC) was initially discovered as a genetic locus associated with the acceptance or rejection of transplanted organs in mice. In 1954, the same genetic system was described in humans by Jean Dausset and Jan van Rood and was called human leukocyte antigens (HLA).
Detailed explanation-4: -The major histocompatibility (MHC) class I antigen presentation pathway plays an important role in alerting the immune system to virally infected cells. MHC class I molecules are expressed on the cell surface of all nucleated cells and present peptide fragments derived from intracellular proteins.
Detailed explanation-5: -Which of the following apply to the protein complex known as major histocompatability complex (MCH)?-MHC is present on every cell in the body.
Detailed explanation-6: -The major histocompatibility complex (MHC) is a group of genes that encode proteins on the cell surface that have an important role in immune response. Their main role is in antigen presentation where MHC molecules display peptide fragments for recognition by appropriate T-cells.
Detailed explanation-7: -Major histocompatibility complex (MHC) is a collection of genes coding for glycoprotein molecules expressed on the surface of all nucleated cells. MHC I molecules are expressed on all nucleated cells and are essential for presentation of normal “self” antigens.