OVERVIEW OF THE IMMUNE SYSTEM
THE GOOD BAD AND UGLY OF THE IMMUNE SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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IgA
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IgG
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IgM
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IgE
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Detailed explanation-1: -IgG is synthesized mostly in the secondary immune response to pathogens. IgG can activate the classical pathway of the complement system, and it also is highly protective. The four subclasses of IgG include IgG1, IgG2, IgG3, and IgG4. IgG1 is around 65% of the total IgG.
Detailed explanation-2: -The major class of immunoglobulin in the blood is IgG, which is a four-chain monomer produced in large quantities during secondary immune responses.
Detailed explanation-3: -IgG1 is the most abundant IgG subclass in human sera and is important for mediating antibody responses against viral pathogens.
Detailed explanation-4: -The secondary antibody response is characterized in its first few days by the production of small amounts of IgM antibody and larger amounts of IgG antibody, with some IgA and IgE.
Detailed explanation-5: -IgG is the most abundant antibody isotype in the blood (plasma), accounting for 70-75% of human immunoglobulins (antibodies). IgG detoxifies harmful substances and is important in the recognition of antigen-antibody complexes by leukocytes and macrophages.
Detailed explanation-6: -IgA is the most abundant antibody isotype in the body, comprising almost 70 percent of the body’s total immunoglobulin.