IMMUNOLOGY

OVERVIEW OF THE IMMUNE SYSTEM

VIROLOGY AND IMMUNITY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which cells produce antibodies against an identified pathogen?
A
T cells
B
B cells
C
Natural killer cells
D
Macrophages
Explanation: 

Detailed explanation-1: -B lymphocytes, also called B cells, create a type of protein called an antibody. These antibodies bind to pathogens or to foreign substances, such as toxins, to neutralize them. For example, an antibody can bind to a virus, which prevents it from entering a normal cell and causing infection.

Detailed explanation-2: -By producing antibodies, B cells are main players in the protective immune response against pathogenic infections. In response to antigens, they mature into antibody-producing plasma cells or into memory B cells, which can quickly be reactivated following secondary challenge.

Detailed explanation-3: -There are two main types of B-cells: plasma cells and memory cells. Both types help protect you from infection and disease. Plasma cells: Plasma cells release antibodies in response to antigens. Once a B-cell becomes a mature plasma cell, it can release up to 2, 000 antibodies per second.

Detailed explanation-4: -T cells can detect the presence of an intracellular pathogen because infected cells display on their surface peptide fragments derived from the pathogen’s proteins. These foreign peptides are delivered to the cell surface by specialized host-cell glycoproteins.

Detailed explanation-5: -B cells have B cell receptors (BCRs) on their surface, which they use to bind to a specific protein. Once the B cells bind to this protein, called an antigen, they release antibodies that stick to the antigen and prevent it from harming the body. Then, the B cells secrete cytokines to attract other immune cells.

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