(A) The loss of his parents
(B) ** The loss of his wife and children
(C) The loss of the presidential election
(D) The loss of failing his law school exam
EXPLANATIONS BELOW
Concept note-1: -Children. Joe Biden fathered four children from two marriages. His firstborn daughter, Naomi Christina Biden, died in 1972, in the same car accident as her mother, and his firstborn son, Joseph “Beau” R. Biden III, died in 2015 from brain cancer.