HYPERSENSITIVITY
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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What is the third phase of a type I hypersensitivity described as involving?
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basophils
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eosinophils
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neutrophils
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fibroblasts
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Explanation:
Detailed explanation-1: -Type I reactions (i.e., immediate hypersensitivity reactions) involve immunoglobulin E (IgE)–mediated release of histamine and other mediators from mast cells and basophils. Examples include anaphylaxis and allergic rhinoconjunctivitis.
Detailed explanation-2: -Definition of type 1 hypersensitivity reaction This is also called an anaphylactic reaction (anaphylaxis – harmful) or allergic reaction. It has two presentations: Immediate reaction: This reaction starts within 5-30 minutes and subsides in 60 minutes. Late phase reaction: This starts in 2-8 hours and lasts 2-3 days.
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