HYPERSENSITIVITY
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Allergic rhinitis
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Poly arteritis nodosa
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Tuberculin hypersensitivity
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Atopic dermatitis
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Contact dermatitis
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Detailed explanation-1: -Type I hypersensitivities include atopic diseases, which are an exaggerated IgE mediated immune responses (i.e., allergic: asthma, rhinitis, conjunctivitis, and dermatitis), and allergic diseases, which are immune responses to foreign allergens (i.e., anaphylaxis, urticaria, angioedema, food, and drug allergies).
Detailed explanation-2: -Atopic dermatitis is a type I IgE-mediated hypersensitivity reaction, but the exact etiology is unknown.
Detailed explanation-3: -Type I hypersensitivity is also known as an immediate reaction and involves immunoglobulin E (IgE) mediated release of antibodies against the soluble antigen. This results in mast cell degranulation and release of histamine and other inflammatory mediators.
Detailed explanation-4: -Anaphylaxis is typically an IgE-mediated (type 1) hypersensitivity reaction that involves the release of numerous chemical mediators from the degranulation of basophils and mast cells after re-exposure to a specific antigen.