IMMUNOGLOBULINS
IMMUNOGLOBULIN STRUCTURE TYPES DISTRIBUTION BIOLOGICAL AND CHEMICAL PROPERTIES
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Type I
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Type II
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Type III
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Type IV
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Detailed explanation-1: -Acute rheumatic fever is a type II hypersensitivity reaction that is a consequence of pharyngeal infection with group A strep (Streptococcus pyogenes), aka strep throat. It is not a direct effect of the bacteria (occurs 2-3 weeks after the infectioin), but is immune mediated.
Detailed explanation-2: -Type II hypersensitivity is typified by a transfusion reaction in which mismatched red blood cells are rapidly destroyed by specific preformed antibodies (anti-ABO or-Rh) and complement.
Detailed explanation-3: -Type I: reaction mediated by IgE antibodies. Type II: cytotoxic reaction mediated by IgG or IgM antibodies. Type III: reaction mediated by immune complexes. Type IV: delayed reaction mediated by cellular response.