MRCP UK EXAMINATIONS

ABDOMINAL

CHRONIC LIVER DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Esophageal varices are a potentially life-threatening complication of cirrhosis. Without treatment, what can occur?
A
hemorrhage
B
portal vein blockage
C
esophageal obstruction
D
death Esophageal varices are a potentially serious complication of cirrhosis. Without treatment, between 25 and 40 percent of people with varices will experience an episode of severe bleeding (hemorrhage) resulting in significant illness or even death.
Explanation: 

Detailed explanation-1: -Esophageal varices are dilated submucosal distal esophageal veins connecting the portal and systemic circulations. They form due to portal hypertension, which commonly is a result of cirrhosis, resistance to portal blood flow, and increased portal venous blood inflow.

Detailed explanation-2: -The more severe the liver damage is and the larger the varices (enlarged veins) are, the greater your risk is for variceal bleeding. About 50 to 60 out of 100 people who have cirrhosis develop varices in the esophagus. Of the people who develop varices, about 15 out of 100 per year will have an episode of bleeding.

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